Studien & Publikationen

Pflaster und Wundheilung neu gedacht

In einem aufschlussreichen Interview verraten Beiersdorf Expertinnen, was ein Pflaster wirksam macht, welche Vorteile die feuchte Wundheilung bietet und wie Innovationen seit 1922 die Wundversorgung verändert haben, um eine bessere Heilung und weniger Narbenbildung zu ermöglichen.

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2016

Kolbe L Biological Cell Protection by Natural Compounds, a Second Line of Defense Against Solar Radiation in: Skin Stress Reponse Pathways, Wondrak G (ed), Springer International Publishing AG, Cham, Switzerland, pp 361-378, 2016
Barroso J, Pfannenbecker U, Adriaens E, Alépée N, Cluzel M, De Smedt A, Hibatallah J, Klaric M, Mewes K, Millet M, Templier M, McNamee P. Cosmetics Europe compilation of historical serious eye damage/ eye irritation in vivo data analysed by drivers of classification to support the selection of chemicals for development and evaluation of alternative methods/strategies: the Draize eye test Reference Database (DRD). Archives of Toxicology 2016 (in press).
Roggenkamp D, Worthmann AC, Sulzberger M, Wenck H, Stäb F, Neufang G: Menthoxypropanediol inhibits nerve-growth-factor-induced nerve fiber sprouting in co-culture models of sensory neurons and skin cells. Exp Dermatol. 2016 Apr 27. doi: 10.1111/exd.13055. [Epub ahead of print]
Traupe B, Fölster H, Max H, Schulz J: Effective axillary malodour reduction by polyquaternium-16-containing deodorants. Int J Cosmet Sci. 2016 Aug 9. doi: 10.1111/ics.12358. [Epub ahead of print]
Choi W, Yin L, Smuda C, Batzer J, Hearing VJ, Kolbe L: Molecular and histological characterization of age spots. Exp Dermatol. 2016 Sep 13. doi: 10.1111/exd.13203. [Epub ahead of print]
Reichert O, Fleming T, Neufang G, Schmelz M, Genth H, Kaever V, Wenck H, Staeb F, Terstegen L, Kolbe L, Roggenkamp D: Impaired Glyoxalase Activity is Associated with Reduced Expression of Neurotrophic Factors and Pro-inflammatory Processes in Diabetic Skin Cells. Exp Dermatol. 2016 Jun 16 doi: 10.1111/exd.13118. [Epub ahead of print]
Fiedler J, Grönniger E, Pfanne A, Brönneke S, Schmidt K, Falk CS, Wenck H, Terstegen L, Thum T, Winnefeld M: Identification of miR-126 as a new regulator of skin aging. Exp Dermatol. 2016 Aug 30. doi: 10.1111/exd.13173. [Epub ahead of print]
Reichert O, Fleming T, Neufang G, Schmelz M, Genth H, Kaever V, Wenck H, Staeb F, Terstegen L, Kolbe L, Roggenkamp D: Impaired Glyoxalase Activity is Associated with Reduced Expression of Neurotrophic Factors and Pro-inflammatory Processes in Diabetic Skin Cells. Exp Dermatol. 2016 Jun 16. doi: 10.1111/exd.13118. [Epub ahead of print]
Gerstel D, Jacques-Jamin C, Schepky A, Cubberley R, Eilstein J, Grégoire S, Hewitt N, Klaric M, Rothe H, Duplan H. Comparison of protocols for measuring cosmetic ingredient distribution in human and pig skin. Toxicol In Vitro. 2016; 34: 153-60.
Huber B, Link A, Linke K, Gehrke SA, Winnefeld M, Kluger PJ. Integration of Mature Adipocytes to Build-Up a Functional Three-Layered Full-Skin Equivalent. Tissue Eng Part C Methods. 22(8): 756-64, 2016
Marx U, Andersson TB, Bahinski A, Beilmann M, Beken S, Cassee FR, Cirit M, Daneshian M, Fitzpatrick S, Frey O, Gaertner C, Giese C, Griffith L, Hartung T, Heringa MB, Hoeng J, de Jong WH, Kojima H, Kuehnl J, Leist M, Luch A, Maschmeyer I, Sakharov D, Sips AJ, Steger-Hartmann T, Tagle DA, Tonevitsky A, Tralau T, Tsyb S, van de Stolpe A, Vandebriel R, Vulto P, Wang J, Wiest J, Rodenburg M, Roth A: Biology-inspired microphysiological system approaches to solve the prediction dilemma of substance testing. ALTEX. 2016; 33(3): 272-321.
Roggenkamp D, Koop U, Filbry A, Keyhanian S, de Kleijn S, Conzelmann S, Neufang G. Vehicle-controlled treatment of xerosis with a topical formulation containing natural moisturizing factors and lipids. Poster P2264, 25th EADV Congress, Vienna 2016
Altgilbers S, Holtzmann U, Worthmann A-C, Neufang G, Rippke F, Grönniger E. The antioxidant Silymarin S protects and activates dermal microcapillaries in vitro. Poster P0498, 25th EADV Congress, Vienna 2016
Neufang G, Rümmelein B, Sögding-Beck K, Reljić D, Demschik G, Rigoni C, Cantú A, Jovanović Z. Dermocosmetic approach in the management of hypersensitive skin - Results of an international study involving 647 patients. Poster P0490, 25th EADV Congress, Vienna 2016
Van Geloven A, Klensang K, Djamil J, Neufang G, Warnke K. Formulations containing Silymarin S and Arctiin significantly improve the elasticity and microvascular structure of ageing skin. Poster P2194, 25th EADV Congress, Vienna 2016
Bormann F, Rodríguez-Paredes M, Hagemann S, Manchanda H, Kristof B, Gutekunst J, Raddatz G, Haas R, Terstegen L, Wenck H, Kaderali L, Winnefeld M, Lyko F. Reduced DNA methylation patterning and transcriptional connectivity define human skin aging. Aging Cell. 2016, 15(3): 563-71.
Meinke MC, Schanzer S, Richter H, Rippke F, Filbry A, Bohnsack K, Patzelt A, Lademann J. Prevention of cutaneous penetration and CD1c+ uptake of pollen allergens by a barrier-enhancing formulation. Skin Pharmacol Physiol 2016, 29: 71-75
Sulzberger M, Fölster H, Sattler M, Rippke F, Grönniger E. Inhibition of Propionibacterium acnes associated biofilm formation by Decanediol. J Dermatol Sci. 2016, 83: 159-161
Klaric M, Pfannenbecker U, Adriaens E, Alepee N, Barroso J, Hibatallah J, Mewes KR, McNamee P. Critical Review of the UN GHS Decision Criteria for Chemicals Causing Irreversible Effects on the Eye/Serious Damage to the Eye: Cosmetics Europe Analysis. 55th Annual Meeting of the Society of Toxicology, New Orleans 2016 (Poster).
Alépée N, Hibatallah J, Klaric M, Mewes KR, Pfannenbecker U, McNamee P. Assessment of cosmetic ingredients in the in vitro reconstructed human epidermis test method EpiSkin™ using HPLC/UPLC-spectrophotometry in the MTT-reduction assay. Toxicology in Vitro 33, 105–117, 2016.
Darvin ME, Schanzer S, Lademann J, Tesch M, Buerger A, Rippke F, Meinke MC. Protective efficacy of a licochalcone A containing sunscreen in the high energy visible spectral range in vivo (abstr.). Exp. Dermatol. 2016, 25: E32
Darvin ME, Schanzer S, Lademann J, Tesch M, Buerger A, Rippke F, Meinke MC. Licochalcone A containing sunscreen protects the skin from carotenoid depletion induced by irradiation with high energy visible light - Results of a double-blind, vehicle-controlled in vivo study. Poster P1795, 25th EADV Congress, Vienna 2016
Sulzberger M, Worthmann A-C, Holtzmann U, Buck B, Jung KA, Schoelermann AM, Rippke F, Stäb F, Wenck H, Neufang G, Grönniger E. Effective treatment for sensitive skin: 4-t-butylcyclohexanol and licochalcone A. JEADV 2016, 30 (Suppl. 1): 9-17
Schoelermann AM, Jung KA, Buck B, Groenniger E, Conzelmann S. Comparison of skin calming effects of cosmetic products containing 4-t-butylcyclohexanol or acetyl dipeptide-1 cetyl ester on capsaicin-induced facial stinging in volunteers with sensitive skin. JEADV 2016, 30 (Suppl. 1): 18-20
Schoelermann AM, Weber TM, Arrowitz C, Rize RL, Qian K, Babcock M. Skin compatibility and efficacy of a cosmetic skin care regimen with licochalcone A and 4-t-butylcyclohexanol in patients with rosacea subtype I. JEADV 2016, 30 (Suppl. 1): 21-27
Kuhlmann M, Ekanayake-Bohling S, Klensang K, Hartkopf C, Saladin S, Wigger-Alberti W. Local tolerability and wound healing properties of two waterproof dressings for post-operative care after minor surgery. Congress of the European Wound Management Association, EWMA, Bremen, Germany, 2016 (Poster sub)
Kuhlmann M, Klensang K, Manger C, Saladin S. Local tolerability, efficacy and acceptability of a corn plaster with salicylic acid in the treatment of corns. FIP World Congress of Podiatry, 2016 (Poster sub)
Schweiger D, Hoff A, Scheede S, Fischer F, Tilsner J, Lüttke J, Neumann Y, Hagens R. Towards a Body Hair Atlas of Women of Caucasian Ethnicity. Int J Cosmet Sci. 38(4): 409-420, 2016
Halm M, Schenke-Layland K, Jaspers S, Wenck H, Fischer F: Visualizing tropoelastin in a long-term human elastic fibre cell culture model. Sci Rep. 2016; 6: 20378.
Kwiatkowski M, Wurlitzer M, Krutilin A, Kiani P, Nimer R, Omidi M, Mannaa A, Bussmann T, Bartkowiak K, Kruber S, Uschold S, Steffen P, Lübberstedt J, Küpker N, Petersen H, Knecht R, Hansen NO, Zarrine-Afsar A, Robertson WD, Miller RJ, Schlüter H: Homogenization of tissues via picosecond-infrared laser (PIRL) ablation: Giving a closer view on the in-vivo composition of protein species as compared to mechanical homogenization. J Proteomics. 134: 193-202, 2016.
Mellem D, Fischer F, Jaspers S, Wenck H, Rübhausen M: Quality Saving Mechanisms of Mitochondria during Aging in a Fully Time-Dependent Computational Biophysical Model. PLoS One. 2016; 11(1): e0146973

2015

Knott A, Achterberg V, Smuda C, Mielke H, Sperling G, Dunckelmann K, Vogelsang A, Krüger A, Schwengler H, Behtash M, Kristof S, Diekmann H, Eisenberg T, Berroth A, Hildebrand J, Siegner R, Winnefeld M, Teuber F, Fey S, Möbius J, Retzer D, Burkhardt T, Lüttke J, Blatt T. Topical treatment with coenzyme Q10-containing formulas improves skin's Q10 level and provides antioxidative effects. Biofactors. 2015; 41(6): 383-90.
Batzer J, Bleckmann A, Lerg H, Schwanke F, Schläger T. The "Dispersal Rate" - a product dependent characteristic to predict the reliability of the calibrated in vitro SPF on WW5 plates. Int J Cosmet Sci. 2016; 38(3): 294-304
Knott A. Benefits of topical Q10 treatment on human skin. The 8th Conference of the International Coenzyme Q10 Association (talk). Meeting in Bologna, October 8-11, 2015.
Winnefeld M. Secretory Micro-RNAs (miRs): New “drivers” of skin aging. MicroRNAs/Genome Editing & END/Optogenetics Europe-2015 Meeting in Cambridge, UK (talk)Fölster-Holst R, Galecka J, Weißmantel S, Dickschat U, Rippke F, Bohnsack K, Werfel T, Wichmann K, Buchner M, Schwarz T, Vogt A, Lademann J, Meinke MC. Birch pollen influence the severity of atopic eczema - prospective clinical cohort pilot study and ex vivo penetration study. Clin Cosmet Investig Dermatol. 8: 539-48, 2015
Keiko Inukai, Waka Ban, Kazuo Inoue: Effective prevention of axillary stress-induced sweating and malodor with antiperspirant/deodorant product in a single-use package, FRAGRANCE JOURNAL, Vol.43, No.8, 30-36 (2015)
Mann T, Eggers K, Rippke F, Terstegen L, Wenck H, Kolbe L. Licochalcone A protects from reactive oxygen species induced by high energy visible light at common ambient solar doses. 24th Congress of the European Academy of Dermatology and Venereology, Copenhagen 2015 (Poster P1514)
Manwaring J, Obringer C, Hewitt N, Schepky A, Gerstel D, Klaric M, Eilstein J, Grégoire S, Duplan H, Jacques-Jamin C, Cubberley R, Rothe H. Partition Coefficient Determinations for Benzoic Acid, Resorcinol and Methyl Paraben in Isolated Human Skin Layers for In Silico Dermal Pen Modeling. 54th Annual Meeting of the Society of Toxicology, San Diego 2015 (Poster).
Jaworska J, Manwaring J, Obringer C, Hewitt N, Schepky A, Gerstel D, Klaric M, Eilstein J, Grégoire S, Duplan H, Jacques-Jamin C, Cubberley R, Rothe H. Cosmetics Europe skin penetration modelling program: K and D measurements of isolated skin layers and isolated SC lipids. Modeling Natural Barriers, Bad Wildbad, Germany, 2015 (Poster).
Hewitt N, Schepky A, Gerstel D, Klaric M, Eilstein J, Grégoire S, Duplan H, Jacques-Jamin C, Cubberley R, Rothe H. Solubility of cosmetics ingredients in 6 different solvents and applicability to skin bioavailability assays. Eurotox 2015, Porto, Portugal (Poster).
Schepky A, Hewitt N, Cubberley R, Duplan H, Eilstein J, Gerstel D, Grégoire S, Jacques-Jamin C, Rothe H. Differences on protocols for skin penetration and Stratum Corneum diffusion/partition coefficients: 54th Annual Meeting of the Society of Toxicology, San Diego 2015 (Poster)
Claire Regazzetti, Gian Marco De Donatis, Houda Hammami Ghorbel, Nathalie Cardot-Leccia, Ambrosetti Damien, Bahadoran Philippe, Bérengère Chignon, Lacour Jean-Philippe, Ballotti Robert, Mahns Andre, Passeron Thierry. Endothelial cells promote pigmentation through endothelin receptor B activation. JID, Accepted for Publication on 29. June 2015
Kuehne A, Emmert H, Soehle J, Winnefeld M, Fischer F, Wenck H, Gallinat S, Terstegen L, Lucius R, Hildebrand J, Zamboni N. Acute Activation of Oxidative Pentose Phosphate Pathway as First-Line Response to Oxidative Stress in Human Skin Cells. Mol. Cell. 59(3): 359-371, 2015
Gehrke S, Schmidt K, Rippke F, Groenniger E, Winnefeld M. Magnolia bark extract (magnolol) protects cells from the hypodermis against UV-induced cell damage. 24th Congress of the European Academy of Dermatology and Venereology, Copenhagen 2015 (Poster P0401)
Sulzberger M, Foelster H, Sattler M, Rippke F, Groenniger E. The antimicrobial decylene glycol prevents and reduces biofilm formation of p. acnes in vitro. 24th Congress of the European Academy of Dermatology and Venereology, Copenhagen 2015 (Poster P0028)
Angelova-Fischer I, Rippke F, Richter D, Filbry A, Fischer TW, Zillikens D. A water-in-oil emollient containing licochalcone A and omega-6-fatty acids reduces the number of relapses after discontinuation of the topical steroid treatment in atopic dermatitis: A double-blind, prospective, vehicle-controlled, left-right comparison study. 24th Congress of the European Academy of Dermatology and Venereology, Copenhagen 2015 (Poster P0205)
Schweiger D, Schoelermann AM, Filbry A, Hamann T, Moser C, Rippke F: Highly efficient and compatible shampoo for use after hair transplant. Clin Cosmet Invest Dermatol. 8: 355-360, 2015.
Šebeková K, Stürmer M, Fazeli G, Bahner U, Stäb F, Heidland A. Is vitamin d deficiency related to accumulation of advanced glycation end products, markers of inflammation, and oxidative stress in diabetic subjects? Biomed Res Int. 2015: 958097.
Hoffmann S, Alepee N, Allen D, Ashikaga T, Cluzel M, Gellatly N, Hibatallah J, Kern P, Klaric M, Kleinstreuer N, Kühnl J, Mewes K, Millet M, Miyazawa M, Phillips E, Teissier S, van Vliet E, Petersohn D: Transatlantic collaboration of Cosmetics Europe with NICEATM/ILS to assess and develop strategy for skin sensitisation safety assessment without animal testing 19th Meeting of the European society for alternatives to animal testing, Linz (Poster)
Neufang G, Keyhanian S, Schoelermann AM, Rippke F: Beneficial role of daily skin care for diabetic patients. 23rd World Congress of Dermatology, Vancouver 2015 (Poster)
Sulzberger M, Worthmann A-C, Jung KA, Buck B, Schoelermann AM, Rippke F, Wolber R, Neufang G, Groenniger E: The combination of TRPV1-antagonist 4-t-butylcyclohexanol and the anti-inflammatory flavonoid licochalcone A effectively improves subjective and objective symptoms of sensitive and irritated skin. 23rd World Congress of Dermatology, Vancouver 2015 (Poster)
Jung KA, Buck B, Benner G, Filbry A, Schoelermann AM: 10% urea containing body lotion improves subjective and objective symptoms of patients suffering from mild to moderate psoriasis: Results of a 4-weeks-treatment in vivo study. 23rd World Congress of Dermatology, Vancouver 2015 (Poster)
Weber TM, Babcock M, Samarin F, Neufang G, Filbry A, Arrowitz C, Rippke F: A novel daily moisturizing body cream reduces flare frequency and extends the time-to-flare for infants and children with mild to moderate atopic dermatitis. 23rd World Congress of Dermatology, Vancouver 2015 (Poster)
Neufang G, Roggenkamp D, Kolbe L, Wenck H, Staeb F, Terstegen L, Reichert O: Diabetes-induced dysfunctions in epidermal keratinocytes. 23rd World Congress of Dermatology, Vancouver 2015 (Poster)
Neufang G, Roggenkamp D, Wenck H, Staeb F, Terstegen L, Kolbe L, Reichert O: UV radiation enhances CXCL5 release in human skin in vitro and in vivo. 23rd World Congress of Dermatology, Vancouver 2015 (Poster)
Weber TM, Samarin F, Babcock MJ, Filbry A, Arrowitz CE, Rippke F: Steroid-free over-the counter eczema skin care formulations reduce risk of flare, prolong time to flare, and reduce eczema symptoms in pediatric patients with atopic dermatitis. J Drugs Dermatol. 14 (5): 478-485, 2015
Jung KA, Buck B, Neufang G, Filbry A, Schoelermann AM: A multifunctional moisturizing repair body lotion improves subjective and objective symptoms of patients suffering from mild to moderate psoriasis: Results of a 4-week-treatment in vivo study (abstr.). J Amer Acad Dermatol. 72 (5) Suppl 1: AB222, 2015
Weber TM, Samarin F, Babcock MJ, Filbry A, Arrowitz CE, Rippke F: A novel daily moisturizing cream for effective management of mild to moderate atopic dermatitis in infants and children (abstr.). J Amer Acad Dermatol. 72 (5) Suppl 1: AB73, 2015
Brönneke S, Brückner B, Söhle J, Siegner R, Smuda C, Stäb F, Wenck H, Kolbe L, Grönniger E, Winnefeld M: Genome-wide expression analysis of wounded skin reveals novel genes involved in angiogenesis. Angiogenesis 18(3): 361-371, 2015
Yin L, Coelho SG, Valencia JC, Ebsen D, Mahns A, Smuda C, Miller SA, Beer JZ, Kolbe L, Hearing VJ: Identification of Genes Expressed in Hyperpigmented Skin using Meta-Analysis of Microarray Datasets. J Invest Dermatol. 2015 Oct;135(10):2455-63.
Reuter H, Gerlach S, Spieker J, Ryan C, Bauch C, Mangez C, Winkler P, Landsiedel R, Templier M, Mignot A, Gerberick F, Wenck H, Aeby P, Schepky A: Evaluation of an optimized protocol using human peripheral blood monocyte derived dendritic cells for the in vitro detection of sensitizers: Results of a ringstudy in five laboratories. Toxicol In Vitro. 29(5):976-986, 2015
Alépée N, Barroso J, De Smedt A, De Wever B, Hibatallah J, Klaric M, Mewes KR, Millet M, Pfannenbecker U, Tailhardat M, Templier M, McNamee P: Use of HPLC/UPLC-spectrophotometry for detection of formazan in in vitro Reconstructed human Tissue (RhT)-based test methods employing the MTT-reduction assay to expand their applicability to strongly coloured test chemicals. Toxicol In Vitro. 29(4):741-61, 2015
Weber TM, Herndon JH Jr, Ewer M, Stephens TJ, Flick I, Filbry A, Neufang G, Schoelermann AM: Efficacy and Tolerability of Steroid-Free, Over-the-Counter Treatment Formulations in Infants and Children With Atopic Dermatitis. J Dermatol Nurses Assoc. 7(1):17-24, 2015
Kühnl J, Roggenkamp D, Gehrke SA, Stäb F, Wenck H, Kolbe L, Neufang G: Licochalcone A activates Nrf2 in vitro and contributes to licorice extract-induced lowered cutaneous oxidative stress in vivo. Exp Dermatol. 24(1):42-47, 2015
Reichert O, Kolbe L, Terstegen L, Staeb F, Wenck H, Schmelz M, Genth H, Kaever V, Roggenkamp D, Neufang G: UV radiation induces CXCL5 expression in human skin. Exp Dermatol. 24(4):309-12, 2015
Hanack C, Moroni M, Lima WC, Wende H, Kirchner M, Adelfinger L, Schrenk-Siemens K, Tappe-Theodor A, Wetzel C, Kuich PH, Gassmann M, Roggenkamp D, Bettler B, Lewin GR, Selbach M, Siemens J: GABA blocks pathological but not acute TRPV1 pain signals. Cell 160(4):759-70; 2015
Stürmer M, Šebeková K, Fazeli G, Bahner U, Stäb F, Heidland A: 25-hydroxyvitamin d and advanced glycation endproducts in healthy and hypertensive subjects: are there interactions? J Ren Nutr. Mar;25 (2): 209-16, 2015
Coelho SG, Valencia JC, Yin L, Smuda C, Mahns A, Kolbe L, Miller SA, Beer JZ, Zhang G, Tuma PL, Hearing VJ: UV exposure modulates hemidesmosome plasticity, contributing to long-term pigmentation in human skin. J Pathol. 236(1):17-29, 2015
Coelho SG, Yin L, Smuda C, Mahns A, Kolbe L, Hearing VJ: Photobiological implications of melanin photoprotection after UVB-induced tanning of human skin but not UVA-induced tanning. Pigment Cell Melanoma Res. 2015 28(2):210-216, 2015
Baumann T., Jovanovic Z., Reuschlein K., Schmidt-Rose T., Max H., Terstegen L., Schweiger D. ABCC11 – a new transporter in apocrine sweat glands. Salivary Glands & Exocrine Biology, Gorden Research Conference, Galveston, Tx, US, February, 2015 (Poster).
Gallinger J., Schweiger D. ABCC11 – the key human anti-odor target. The UK Semiochemistry Network Chemical Signals in Vertebrates, British Workshop XXIII, Cambridge, UK, July 2015 (talk).
Reisinger K, Hoffmann S, Alépée N, Ashikaga T, Barroso J, Elcombe C, Gellatly N, Galbiati V, Gibbs S, Groux H, Hibatallah J, Keller D, Kern P, Klaric M, Kolle S, Kuehnl J, Lambrechts N, Lindstedt M, Millet M, Martinozzi-Teissier S, Natsch A, Petersohn D, Pike I, Sakaguchi H, Schepky A, Tailhardat M, Templier M, van Vliet E, Maxwell G: Systematic evaluation of non-animal test methods for skin sensitisation safety assessment. Tox in vitro. Feb; 29 (1):259-270, 2015
Kuhlmann M, Saladin S, Klensang K, Conzelmann S. Capsaicin Heat Plaster in the treatment of muscular back pain. Results of a non-interventional observational study. 63rd International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, Budapest, Hungary 2015; Planta Med 2015; 81 - PM_03
Streicher H, Anti-Staining Technology in anti-perspirants: Innovation from the consumer to the product, XXIV Congreso Nacional de Quimica Cosmetica, Cozumel, Mexico 2015

2014

Rovida C, Alépée N, Api AM, Basketter DA, Bois FY, Caloni F, Corsini E, Daneshian M, Eskes C, Ezendam J, Fuchs H, Hayden P, Hegele-Hartung C, Hoffmann S, Hubesch B, Jacobs MN, Jaworska J, Kleensang A, Kleinstreuer N, Lalko J, Landsiedel R, Lebreux F, Luechtefeld T, Locatelli M, Mehling A, Natsch A, Pitchford JW, Prater D, Prieto P, Schepky A, Schuurmann G, Smirnova L, Toole C, van Vliet E, Weisensee D, Hartung T: Integrated Testing Strategies (ITS) for safety assessment. ALTEX. 2014
Yin L, Coelho SG, Ebsen D, Smuda C, Mahns A, Miller SA, Beer JZ, Kolbe L, Hearing VJ. Epidermal gene expression and ethnic pigmentation variations among individuals of Asian, European and African ancestry. Exp Dermatol. 2014 Oct;23(10):731-5.
Ito S(1), Gerwat W, Kolbe L, Yamashita T, Ojika M, Wakamatsu K. Human tyrosinase is able to oxidize both enantiomers of rhododendrol. Pigment Cell Melanoma Res. 2014 Nov; 27(6):1149-53
Schepky A.: An Overview of the Cosmetics Europe Skin Bioavailability and Metabolism project. Presentation at the 9th World Congress on Alternatives and Animal Use in the Life Sciences, Prague 2014.
Schepky A.: Comparison of protocols measuring stratum corneum diffusion/partition coefficients and skin penetration with focus on sensitizers. Presentation at the ERGECD, Paris, 2014
Weber TM, Filbry A, Schoelermann AM, Rippke F: Efficacy and skin compatibility of a therapeutic moisturizer in keratosis pilaris. 23rd Congress of the European Academy of Dermatology and Venereology, Amsterdam 2014 (Poster no. 1396)
Mann T, Gerwat W, Batzer J, Rippke F, Sun W, Scherner C, Staeb F, Wenck H, Roehm K-H, Kolbe L: Modulation of human skin pigmentation by inhibitors of human tyrosinase. 23rd Congress of the European Academy of Dermatology and Venereology, Amsterdam 2014 (Poster no. 1526)
Grönniger E, Worthmann AC, Sulzberger M, Roggenkamp D, Jung KA, Buck B, Wolber R, Neufang G: TRPV1 antagonist 4-t-butylcyclohexanol inhibits capsaicin induced nerve fiber activation in vitro and in vivo (abstr.). J. Invest. Dermatol. 2014, 134: S102
Angelova-Fischer I, Neufang G, Jung K, Fischer TW, Zillikens D: A randomized, investigator-blinded efficacy assessment study of stand-alone emollient use in mild to moderately severe atopic dermatitis flares. J. Eur. Acad. Derm. Venereol. 2014, 28 (Suppl. 3): 9-15
Kowcz A, Schneider G, Pape W, Weber T: Bench to Beauty Counter: Development of Cosmeceuticals. In: Cosmeceuticals in Clinical Practice; Farris, PK, ed. Wiley-Balckwell: Oxford 2014; pp 11-22
Pfannenbecker U.: In vitro phototoxicity testing: 16 years of experience with a test strategy using the 3T3 Neutral Red Uptake Phototoxicity Test (3T3 NRU PT) and the EpiDerm Phototoxicity Test. Presentation at the 9th World Congress on Alternatives and Animal Use in the Life Sciences, Prague 2014
McNamee P. Alépée N, Hibatallah J, Klaric M, Mewes K, Pfannenbecker U: Continued developments in the Cosmetics Europe Eye Irritation Task Force strategy and programme for prediction and assessment of ocular irritancy. 9th World Congress on Alternatives and Animal Use in the Life Sciences, Prague 2014 (Poster)
Alépée N, Barroso J, De Smedt A, De Wever B, Mewes K, Millet M, Pfannenbecker U, Tailhardat M, Templier M, McNamee P: Use of HPLC/UPLC-photometry for detection of formazan in in vitro Reconstructed human Tissue (RhT)- based test methods to expand their applicability to strongly coloured test substances. 9th World Congress on Alternatives and Animal Use in the Life Sciences, Prague 2014 (Poster)
Adriaens E, Barroso J, Eskes C, Hoffmann S, McNamee P, Alépée N, Bessou-Touya S, De Smedt A, De Wever B, Pfannenbecker U: Retrospective analysis of the Draize test for serious eye damage/eye irritation: importance of understanding the in vivo endpoints under UN GHS / EU CLP for the development and evaluation of in vitro test methods. 9th World Congress on Alternatives and Animal Use in the Life Sciences, Prague 2014 (Poster)
Barroso J, Alépée N, Cole T, Eskes C, Freeman SJ, Liška R, McNamee P, Pfannenbecker U, Reus AA, Rubingh CM, Schaeffer MW, Zuang V: EURL ECVAM – Cosmetics Europe prospective validation study of Reconstructed human Tissue-based test methods for serious eye damage/eye irritation testing. 9th World Congress on Alternatives and Animal Use in the Life Sciences, Prague 2014 (Poster)
McNamee P, Alépée N, Barroso J,4, De Smedt A, De Wever B, Hibatallah J, Klaric M, Mewes K, Millet M, Pfannenbecker U, Tailhardat M, Templier M: The importance of understanding drivers of irritation in vivo for selection of chemicals used in the development and evaluation of in vitro serious eye damage/eye irritation assays: Cosmetics Europe analysis. 9th World Congress on Alternatives and Animal Use in the Life Sciences, Prague 2014 (Poster)
Barroso J, Alépée N, De Smedt A, De Wever B, Hibatallah J, McNamee P, Mewes K, Millet M, Pfannenbecker U, Tailhardat M, Templier M: The Importance of Understanding Drivers of Irritation In Vivo for Selection of Chemicals Used in the Development and Evaluation of In Vitro Eye Irritation Assays: Cosmetics Europe Analysis. SOT, Phoenix 2014 (Poster)
Reichert O, Terstegen L, Staeb F, Wenck H, Neufang G, Kolbe L, Roggenkamp D. Diabetes mellitus induces alterations in insulin sensitivity, release of pro-inflammatory cytokines and antioxidant capacity of epidermal keratinocytes (Abstr). J Invest Dermatol. 2014, 134 (S1): S6
Reichert O, Roggenkamp D, Kolbe L, Staeb F, Terstegen L, Wenck H, Neufang G. Fibroblasts contribute to the increased expression of CXCL5 in human skin after UV exposure. 41st Annual Meeting of the Arbeitsgemeinschaft Dermatologische Forschung
Hewitt N., Cubberley R., Duplan H., Eilstein J., Gerstel D., Grégoire S., Jacques-Jamin C., Klaric M., Rothe H. Schepky A. Comparison of protocols measuring stratum corneum diffusion/partition coefficients and skin penetration. WC9, Poster 60
Mann T, Gerwat W, Wenck H, Röhm KH, Kolbe L. Mode of action of rhododendrol, raspberry ketone, 4-butylresorcinol and other inhibitors of human tyrosinase (Abstr.). Pigment Cell Melanoma Res. 2014, Sep; 27(5):937
Yin L, Coelho SG, Ebsen D, Smuda C, Mahns A, Miller SA, Beer JZ, Kolbe L, Hearing VJ: Epidermal gene expression and ethnic pigmentation variations among individuals of Asian, European and African ancestry. Exp Dermatol. 23:731-735, 2014
Iwen KA, Priewe AC, Winnefeld M, Rose C, Siemers F, Rohwedel J, Cakiroglu F, Lehnert H, Schepky A, Klein J, Kramer J. Gluteal and abdominal subcutaneous adipose tissue depots as stroma cell source: gluteal cells display increased adipogenic and osteogenic differentiation potentials. Exp Dermatol. 23(6):395-400, 2014
Johansson H, Rydnert F, Kühnl J, Schepky A, Borrebaeck C, Lindstedt M. Genomic allergen rapid detection in-house validation--a proof of concept.Toxicol Sci. 2014 Jun;139(2):362-70
Roggenkamp D, Worthmann AC, Sulzberger M, Kolbe L, Neufang G. TRPM8 agonist menthoxypropanediol reduces NGF expression and neurite outgrowth in a coculture model of sensory neurons and dermal fibroblasts (Abstr.). J Invest Dermatol. 2014 May; 134 (S1): S22
Thiessen A, Terstegen L, Stäb F, Wenck H, Kolbe L and Mahns A. Effect of 3oxo-glycyrrhetinic acid on tyrosinase and trp1 protein in normal human melanocytes (Abstr.). J Invest Dermatol. 2014 May; 134 (S1): S128
Weber TM, Babcock MJ, Herndon JH, Filbry AW, Scherdin U, Rippke F. Steroid-free emollient formulations reduce symptoms of eczema and improve quality of life. J. Drugs Dermatol. 2014 May, 13 (5): 589-595
Weber TM, Filbry A, Schoelermann AM, Rippke F, Scherdin U. A daily moisturizer and a steroid-free acute therapy emollient cream reduce the symptoms of atopic dermatitis in babies and children with mild to moderate eczema lesions (Abstr.) J. Am. Acad. Dermatol. 2014 May, 70 (5), Suppl. 1: AB66
Hiddemann S, Schoelermann AM, Neufang G, Weber T, Scherdin U. Combining an TRPV1-antagonist with the antiinflammatory flavonoid licochalcone A improves subjective and objective symptoms of sensitive skin: Results of 2 double-blind, vehicle-controlled in vivo studies (Abstr.). J. Am. Acad. Dermatol. 2014 May, 70 (5), Suppl. 1: AB29
Djamil J, Buerger A, Rippke F, Degwert J, Weber T. Biophysical effects of a novel in-shower skin care formulation with 5% dexpanthenol - Results of a vehicle-controlled in vivo study (Abstr.). J. Am. Acad. Dermatol. 2014 May, 70 (5), Suppl. 1: AB29
Moser C, Rippke F, Schoelermann A, Schweiger D. Highly efficient and compatible hypertolerant shampoo (Abstr.). Exp. Dermatol. 2014 March, 23 (3): e13-e14
Baumann T, Bergmann S, Schmidt-Rose T, Max H, Martin A, Enthaler B, Terstegen L, Schweiger D, Kalbacher H, Wenck H, Jedlitschky G, Jovanovic Z. Glutathione-conjugated sulfanylalkanols are substrates for ABCC11 and γ-glutamyl transferase 1: a potential new pathway for the formation of odorant precursors in the apocrine sweat gland. Exp Dermatol. 2014 Apr;23(4):247-52
Meyer S, Peters N, Mann T, Wolber R, Pörtner R, Nierle J. In vitro efficacy and release study with anti-inflammatory drugs incorporated in adhesive transdermal drug delivery systems. J Pharm Sci. 2014 Apr;103(4):1142-8
Meyer S, Heinsohn G, Wolber R, Pörtner R, Nierle J. Confocal Raman investigation of diffusion processes in monolithic type transdermal drug delivery systems. Drug Deliv. 2014 Mar 3. [Epub ahead of print]
Helt C.v., Martin SF, Schepky A and Kühnl, J. Tolerogenic DC activation as an additional aspect in skin sensitization assays. World Immune Regulation Meeting, Davos, Poster presentation
Koop U, Bretschneider T, Clemann S, Jaspers S: Skin Aging – Microrelief and Wrinkle Measurements, Handbook of Cosmetic Science and Technology, Fourth Edition, edited by André O. Barel, Marc Paye, Howard I. Maibach, CRC Press, 2014, Chapter 20, p 251-262
Gugerell A, Kober J, Laube T, Walter T, Nürnberger S, Grönniger E, Brönneke S, Wyrwa R, Schnabelrauch M, Keck M. Electrospun poly(ester-Urethane)- and poly(ester-Urethane-Urea) fleeces as promising tissue engineering scaffolds for adipose-derived stem cells. PLoS One. 2014 Mar 4;9(3): e90676
Achterberg VF, Buscemi L, Diekmann H, Smith-Clerc J, Schwengler H, Meister JJ, Wenck H, Gallinat S, Hinz B. The nano-scale mechanical properties of the extracellular matrix regulate dermal fibroblast function. J Invest Dermatol. 2014 Jul;134(7): 1862-72
Sondersorg AC(, Busse D, Kyereme J, Rothermel M, Neufang G, Gisselmann G, Hatt H, Conrad H. Chemosensory Information Processing between Keratinocytes and Trigeminal Neurons. J Biol Chem. 2014 Jun 20;289(25): 17529-17540
Ennen J, Degwert J, Duttiné, M, Gerlach N, Jassoy, C, Jünger M, Matthies, W, Mehling A, Merk H; Rossow, U; Welzel J; Wigger-Alberti W; Wilhelm, K-P: Studies on the Skin Compatibility of Cosmetics Involving Human Subjects – Study Portfolio and Test Strategy, IFSCC Magazine 1: 1-5, 2014
Egbert M, Ruetze M, Sattler M, Wenck H, Gallinat S, Lucius R, Weise JM: The matricellular protein periostin contributes to proper collagen function and is downregulated during skin aging. J Dermatol Sci. 73(1):40-8, 2014
Gerstel D, Schepky A, Hewitt NJ, Eilstein J, Grégoire S, Duplan H, Jacques-Jamin C, Rothe H, Cubberley R, Klaric M. The Cosmetics Europe skin bioavailability project: Project status and goals. 14th PPP Conference, La Grande Motte 2014, Poster 69
Basketter DA, Alépée N, Ashikaga T, Barroso J, Gilmour N, Goebel C, Hibatallah J, Hoffmann S, Kern P, Martinozzi-Teissier S, Maxwell G, Reisinger K, Sakaguchi H, Schepky A, Tailhardat M, Templier M. Categorization of chemicals according to their relative human skin sensitizing potency. Dermatitis. 2014 Jan-Feb;25(1):11-21
Alépée N, Bahinski A, Daneshian M, De Wever B, Fritsche E, Goldberg A, Hansmann J, Hartung T, Haycock J, Hogberg H, Hoelting L, Kelm JM, Kadereit S, McVey E, Landsiedel R, Leist M, Lübberstedt M, Noor F, Pellevoisin C, Petersohn D, Pfannenbecker U, Reisinger K, Ramirez T, Rothen-Rutishauser B, Schäfer-Korting M, Zeilinger K, Zurich MG: State-of-the-art of 3D cultures (organs-on-a-chip) in safety testing and pathophysiology. ALTEX. 2014;31(4):441-77
Adriaens E, Barroso J, Eskes C, Hoffmann S, McNamee P, Alépée N, Bessou-Touya S, De Smedt A, De Wever B, Pfannenbecker U, Tailhardat M, Zuang V: Retrospective analysis of the Draize test for serious eye damage/eye irritation: importance of understanding the in vivo endpoints under UN GHS/EU CLP for the development and evaluation of in vitro test methods. Archives of Toxicology, 88, 701–723, 2014

2013

Kern, MJ, Gautreau, O, Saladin, S. The SAM Pre-Mapping Tool: Efficient rapid profiling for fast and reliable sensory screening of a high number of products. Pangborn Sensory Science Symposium, August 2013, Poster
Schipunov E, Rapp C, Schmidt C: Transition from wormlike micelles to multilamellar vesicles in cosmetic surfactant systems. 46th Biennal Meeting of the Colloid Society, Paderborn Sept 23-25, 2013, Poster
Pfannenbecker U, Bessou-Touya S, Faller C, Harbell J, Jacob T, Raabe H, Tailhardat M, Alépée N, deSmedt A, deWever B, Jones P, Kaluzhny Y, LeVarlet B, McNamee P, Marrec-Fairley M, Van Goethem F: Cosmetics Europe multi-laboratory pre-validation of the EpiOcular™ reconstituted human tissue test method for the prediction of eye irritation. Toxicology in Vitro, 27, 619–626, 2013.
Alépée N, Bessou-Touya S, Cotovio J, De Smedt A., De Wever B., Faller C, Jones P, Le Varlet, B., Marrec-Fairley, M., Pfannenbecker, U., Tailhardat M, Van Goethem F, McNamee P, 2013. Cosmetics Europe multi-laboratory prevalidation of the SkinEthic™ reconstituted human corneal epithelium test method for the prediction of eye irritation. Toxicology in Vitro, 27, 1476–1488.
Moyal D, Alard V, Bertin C, Boyer F, Brown MW, Kolbe L, Matts P, Pissavini M: The revised COLIPA in vitro UVA method. Int J Cosmet Sci. 2013 Feb;35(1): 35-40
Cordes P, Sun W, Wolber R, Kolbe L, Klebe G, Röhm KH. Expression in non-melanogenic systems and purification of soluble variants of human tyrosinase. Biol Chem. 2013 May;394(5):685-93.
Ito S, Pilat A, Gerwat W, Skumatz CMB, Ito M, Kiyono A, Zadlo A, Nakanishi Y, Kolbe L, Burke J, Sarna T, Wakamatsu, K. Photoaging of human retinal pigment epithelium is accompanied by oxidative modifications of its eumelanin. Pigment Cell Melanoma Res. 2013 May;26(3):357-66.
Mann T, Gerwat W, Batzer J, Sun W, Scherner C, Stäb F, Wenck H, Röhm K-H, Kolbe L. Modulation of human skin pigmentation by inhibitors of human tyrosinase. International Investigative Dermatology, Edinburgh, Poster 1398
Roggenkamp D, Köpnick S, Stäb F, Wenck H, Schmelz M, Neufang G. Crosstalk of nerve endings and keratinocytes in an innervated skin model: implications for atopic dermatitis. International Investigative Dermatology, Edinburgh, Poster 735
Kolbe L. 4-n-butylresorcinol: a highly effective tyrosinase inhibitor that reduces hyperpigmentation. Annual Meeting of the British Association of Dermatologists, Liverpool, July 2013
Deing V, Kühnl J, Roggenkamp D, Gruschka A, Stäb F, Wenck H, Neufang G. Characterization of the oxytocin system in human skin. 12. ADF, Workgroup Dermatoendocrinology, Dessau, Oral Presentation and Poster
Deing V, Roggenkamp D, Kühnl J, Gruschka A, Stäb F, Wenck H, Neufang, G. A new role of the oxytocin system in human skin stress responses and implications for atopic dermatitis10th meeting of the German Endocrine Brain Immune Network
Thiessen A, Terstegen L, Stäb F, Wenck H, Kolbe L, Mahns A. 3oxo-Glycyrrhetinic acid induces melanogenesis in NHM via posttranslational mechanism. Annual Meeting of the European Society for Pigment Cell Research, Lisbon, Oral Presentation and Poster
Deing V, Roggenkamp D, Kühnl J, Rippke F, Gruschka A, Stäb F, Wenck H, Neufang G. The oxytocin system in primary human skin cells: Effects on proliferation and stress responses with implications for atopic dermatitis. 22nd EADV Congress, Istanbul 2013, Poster P194
Hagemann S, Grönniger E, Schläger T, Holtzmann U, Söhle J, Rippke F, Conzelmann S, Schepky A, Stäb F, Wenck H, Winnefeld M. Magnolia Bark Extract induceslipofilling effects in vitro. 22nd EADV Congress, Istanbul 2013, Poster P389
Akhiani M, Hiddemann S, Leneveu-Duchemin M-C, Vietzke J-P, Rippke F, Schepky A. Appropriate skin cleansing enhances the epidermal bioavailability of dermocosmetic anti-acne actives decanediol and licochalcone A. 22nd EADV Congress, Istanbul 2013, Poster P039
Batzer J, Eggers K, Filbry A, Neufang G, Rippke F, Kolbe L. Induction of reactive oxygen species by visible light and inhibition by Glycyrrhiza inflata extract rich in licochalcone A22nd EADV Congress, Istanbul 2013, Poster P1381
Roggenkamp D, Köpnick S, Stäb F, Wenck H, Schmelz M, Neufang G. An innervated skin model to study the neurocutaneous crosstalk in atopic dermatitis. Neuroscience 2013, San Diego, Poster 741.10
Gehrke S., Brueckner B., Schepky A, Klein J, Iwen A, Bosch T., Wenck H, Winnefeld M, Hagemann S. Epigenetic Regulation of Depot-Specific Gene Expression in Adipose Tissue. PloSOne Volume 8, Issue 12, e825162013, 2013
Raddatz G, Hagemann S, Aran D, Söhle J, Kulkarni PP, Kaderali L, Hellman A, Winnefeld M, Lyko F.: Aging is associated with highly defined epigenetic changes in the human epidermis. Epigenetics Chromatin. 2013 Oct 31;6(1):36
Schmidt-Rose T, Lehmbeck F, Bürger A, Windisch B, Keyhani R, Max H: Efficient sweat reduction of three different antiperspirant application forms during stress-induced sweating. Int J Cosmet Sci. 35(6):622-631, 2013
Jovanovic Z, ABCC11-The Key Anti-Odor Target. Variations of Hair and Skin Conference, Princeton, US, November 2013.
Jovanovic Z, The Key Anti-Odor Target. 15th Bad Herrenalber Barriere- und Transportertage, Bad Herrenalb, May, 2013
Deing V, Roggenkamp D, Kühnl J, Gruschka A, Stäb F, Wenck H, Bürkle A, Neufang G: Oxytocin modulates proliferation and stress responses of human skin cells: implications for atopic dermatitis. Exp Dermatol. 22: 399-405, 2013
Berroth A, Kühnl J, Kurschat N, Schwarz A, Stäb F, Schwarz T, Wenck H, Fölster-Holst R, Neufang G: Role of fibroblasts in the pathogenesis of atopic dermatitis. J Allergy Clin Immunol. 2013 Jun;131:1547-1554, 2013
Enthaler B, Bussmann T, Pruns JK, Rapp C, Fischer M, Vietzke JP: Influence of various on-tissue washing procedures on the entire protein quantity and the quality of matrix-assisted laser desorption/ionization spectra. Rapid Commun Mass Spectrom 27: 878-84, 2013.
Angelova-Fischer I, Rippke F, Fischer TW, Neufang G, Zillikens D: A double-blind, randomized, vehicle-controlled efficacy assessment study of a skin care formulation forimprovement of mild to moderately severe acne. JEADV 27 (Suppl. 2), 6–11, 2013
Ruetze M, Gallinat S, Wenck H, Knott A: Quantification of cyclobutane pyrimidine dimers in human epidermal stem cells. Methods Mol Biol. 989:99-108, 2013
Alépée N, Bessou-Touya S, Cotovio J, De Smedt A, De Wever B, Faller C, Jones P, Le Varlet B, Marrec-Fairley M, Pfannenbecker U, Tailhardat M, Van Goethem F, McNamee P: 2012. Cosmetics Europe multi-laboratory pre-validation of the SkinEthic™ reconstituted human corneal epithelium test method for the prediction of eye irritation. Toxicology In Vitro: 27, 1476-1488, 2013
Schweiger D, Rippke F, Drescher P, Braren S, Lüttke J, Filbry A, Max H: Highly Efficient Rinse-Off/Leave-On Scalp Care Treatments to Reduce Moderate to Severe Dandruff. Journal of Cosmetics, Dermatological Sciences and Applications 2013, 3(1), 46-55.
Schweiger D, Baufeld C, Drescher P, Oltrogge B, Höpfner S, Mess A, Lüttke J, Rippke F, Filbry A, Max H: Efficacy of a New Tonic Containing Urea, Lactate, Polidocanol, and Glycyrrhiza inflata Root Extract in the Treatment of a Dry, Itchy, and Subclinically Inflamed Scalp. Skin Pharmacol Physiol 2013, 26, 108-118
Baumann T, Jovanovic Z, Enthaler B, Schmidt-Rose T, Max H, Martin A, Terstegen L, Schweiger D, ABCC11 – as key anti-odor target. 1st International Workshop on Odor Spaces Hannover, Sept, 2013, Poster 17
Sommer N, Sattler M, Weise JM, Wenck H, Gallinat S, Fischer F: A tissue-engineered human dermal construct utilizing fibroblasts and transforming growth factor β1 to promote elastogenesis. Biotechnol J 8: 317-26, 2013
Tang S, Lucius R, Wenck H, Gallinat S, Weise JM: UV-mediated downregulation of the endocytic collagen receptor, Endo180, contributes to accumulation of extracellular collagen fragments in photoaged skin. J Dermatol Sci. 2013 70:42-8, 2013
Roggenkamp D, Köpnick S, Stäb F, Wenck H, Schmelz M, Neufang G: Epidermal Nerve Fibers Modulate Keratinocyte Growth via Neuropeptide Signaling in an Innervated Skin Model. J Invest Dermatol. 2013 133:1620-8, 2013
Hildebrand J, Grundhoff A, Gallinat S, Wenck H, Knott A: MicroRNA Profiling During Human Keratinocyte Differentiation Using a Quantitative Real-Time PCR Method. Methods Mol Biol. 961:193-200, 2013
Kolbe L, Mann T, Gerwat W, Batzer J, Ahlheit S, Scherner C, Wenck H, Stäb F: 4-n-butylresorcinol, a highly effective tyrosinase inhibitor for the topical treatment of hyperpigmentation. J Eur Acad Dermatol Venereol. 27 Suppl 1:19-23, 2013
Mess A, Enthaler B, Fischer M, Rapp C, Pruns JK, Vietzke JP: A novel sampling method for identification of endogenous skin surface compounds by use of DART-MS and MALDI-MS. Talanta 103: 398-402, 2013
Enthaler B, Trusch M, Fischer M, Rapp C, Pruns JK, Vietzke JP: MALDI imaging in human skin tissue sections: focus on various matrices and enzymes. Anal Bioanal Chem. 405(4):1159-70, 2013
Ruetze M, Knauer T, Gallinat S, Wenck H, Achterberg V, Maerz A, Deppert W, Knott A: A novel niche for skin derived precursors in non-follicular skin. J Dermatol Sci. 69:132-9. 2013
Diercks BP, Hauschildt I, Stäb F, Wenck H, Döring O, Peters N: IL-10 promotes secretion of S100A8/A9 from human monocytes trough an inclusion in plasma membranes. Scand J Immunol 77:169-70, 2013
Kuhlmann M, Kausch M, Span P, Conzelmann S. Treatment of very dry and cracked skin of the feet. Skin care performance, efficacy and skin compatibility of a Foot Care Ointment. FIP World Congress of Podiatry, Rome Italy, Oct 2013, Poster
Kuhlmann M, Span P, Conzelmann S. Treatment of very dry and rough skin of the feet. Skin care performance, efficacy and skin compatibility of a 10% Urea Foot Cream. Annual Conference of the Society of Chiropodists and Podiatrists, Liverpool UK, Nov 2013, Poster

2012

Kindl G , Ruppert S: Sonnenschutz - Ein pharmazeutisch-dermatologischer Leitfaden, Govi Verlag, Eschborn 2012
Hagens R: Letter to the editor. J Cosmet Sci. 63:409-12, 2012
Winnefeld M, Lyko F: The aging epigenome: DNA methylation from the cradle to the grave. Genome Biol. 2012 Jul 30;13(7):165.
Spörl F, Korge S, Jürchott K, Wunderskirchner M, Schellenberg K, Heins S, Specht A, Stoll C, Klemz R, Maier B, Wenck H, Schrader A, Kunz D, Blatt T, Kramer A: Krüppel-like factor 9 is a circadian transcription factor in human epidermis that controls proliferation of keratinocytes. Proc Natl Acad Sci U S A. 2012 Jul 3;109(27):10903-8
Hagemann S, Brönneke S, Winnefeld M: Implications of epigenetic mechanisms for vascular development and disease (editorial) Epigenomics 2012, Oct;4(5):475-7.
Söhle J, Machuy N, Smailbegovic E, Wessel S, Gonda L, Wenck H, Stäb F, Winnefeld M: Identification of New Genes Involved in Human Adipogenesis and Fat Storage. PLoS One 7: e31193, 2012.
Winnefeld M, Brueckner B, Grönniger E, Stäb F, Wenck H, Lyko F: Stable ethnic variations in DNA methylation patterns of human skin. J Invest Dermatol. 132:466-8, 2012
Winnefeld M: Aging and Chronic Sun Exposure Cause Distinct Epigenetic Changes in Human Skin. Oral presentation at 2nd international conference on Variations of Hair & Skin: Ethnicity, Age & Health.2011, Princeton, USA
Kolbe L: How much sun protection is needed?: Are we on the way to full-spectrum protection? J Invest Dermatol. 132:1756-7, 2012
Hildebrand J, Spörl F, Korge S, Gallinat S, Wenck H, Deppert W, Knott A, Blatt T: Cell cycle regulator Cdkn1c (p57/KIP2) shows distinct expression in epidermal differentiation. Eur J Dermatol. 2012 Sep-Oct;22(5):694-6.
Reinheimer K, Grosso M, Hetzel F, Kübel J, Wilhelm M: Fourier Transform Rheology as an innovative morphological characterization technique for the emulsion volume average radius and its distribution. Journal of Colloid and Interface Science 2012 [Epub ahead of print]
Reinheimer K, Grosso M, Kübel J, Hetzel F, Wilhelm M: Fourier Transform Rheology as a noninvasive characterization technique for emulsions. Proceedings of the 6th International Symposium on Food Rheology and Structure (ISFRS); Kerschensteiner Verlag 45 (2012)
Schrader A, Siefken W, Breitenbach U, Gatermann C, Sperling G, Biernoth T, Scherner C, Stäb F, Wenck H, Wittern K-P, Blatt T: Effects of Glyceryl Glucoside on AQP3 Expression, Barrier Function and Hydration of Human Skin. Skin Pharmacol Physiol 25: 192-199, 2012
Aeby P, Alépée N, Ashikaga T, Bessou-Touya S, Dufour E, Gerberick F, Gilmour N, Goebel C, Kern P, Marrec-Fairley M, Martinozzi-Teissier S, Maxwell G, Sakaguchi H, Scheel J, Schepky A, Reisinger K, Tailhardat M, Winkler P: The Colipa Research and Method Development Program for identifying and Characterizing Skin Sensitizers without Animal Testing. ALTEX Proceedings, 2012
Schepky A, Wenck H, Reuter H: Considerations for the Development of an Integrated Testing Stragegy for Skin Sensitization. ALTEX Proceedings, 2012
Prager W, Bohnsack K, Koop U, Zschocke I, Hiddemann S, Leneveu-Duchemin M-C, Rippke F. Patient benefits of four new anti-wrinkle face care formulations containing glycine saponin and hyaluronic acid applied in comparison to vehicle in the course of a hyaluron filler injection therapy. EADV, Prag 2012, Poster 240
Koop U, Lorenz J, Hiddemann S, Conzelmann S, Bohnsack K, Rippke F. A novel, extra mild skin cleansing milk synergistically enhances the efficacy of facial moisturizing creams and improves skin condition. EADV, Prag 2012, Poster 241
Schweiger D, Filbry A, Oltrogge B, Schimana-Bernd M, Rippke F, Leneveu-Duchemin MC, Max H, Schmidt-Rose T: Stimulation of hair roots by topical treatment with L-carnitine, creatine and Glycyrrhiza inflata root extract, EADV, Prag 2012, Poster 565
Schweiger D, Drescher P, Rippke F, Max H, Leneveu-Duchemin MC, Hillemann T, Filbry A: Fighting dandruff with a topical rinse-off/leave-on product combination, EADV, Prag 2012, Poster 568
Filbry A, Baufeld C, Drescher P, Oltrogge B, Rippke F, Leneveu-Duchemin MC, Schmidt-Rose T, Max H, Schweiger D: Efficacy of a new tonic containing urea, polidocanol and Glycyrrhiza inflata root extract against symptoms of dry and itchy scalp, EADV, Prag 2012, Poster 569
Bohnsack K, Koop U, Hiddemann S, Kolbe L, Rippke F. Pigmentation reducing efficacy and tolerability of six new face care formulations containing 4-n-butylresorcinol. EADV, Prag 2012, Poster 864
Bohnsack K, Koop U, Filbry A, Schoelermann A, Rippke F, Kausch M. Advances in the treatment of xerosis: Novel humectants provide superior moisturization compared to common treatments. EADV, Prag 2012, Poster 1052
Filbry A, Rippke F, Leneveu-Duchemin MC, Max H, Schweiger D: Highly effective anti-dandruff shampoo/tonic combination, EHRS, Barcelona 2012, Poster 67
Filbry A, Rippke F, Leneveu-Duchemin MC, Max H, Schmidt-Rose T, Schweiger D: Fighting hair thinning with an energizing and anti-inflammatory hair tonic, EHRS, Barcelona 2012, Poster 68
Filbry A, Rippke F, Leneveu-Duchemin MC, Max H, Schweiger D: New leave-on tonic improves dry, itchy and inflamed scalp symptoms, EHRS, Barcelona 2012, Poster 69
Haag M, Hamann T, Kulle A, Riepe F, Blatt T, Wenck H, Holterhus P-M, Peirano, R: Age and skin site related differences in steroid metabolism in male skin point to a key role of sebocytes in cutaneous hormone metabolism. Dermato-Endocrinology 4:1, 1-7, 2012
Goodman JI, Hayes WA, Korte F, Lotti M, Pariza M, Rulis A, Satoh T, Schepky A: Regulatory Toxicology and Pharmacology. SciVerse ScienceDirect, 2012
Tschierske, N, Emeis, D, Biel, SS: Efficacy loss of antimicrobial actives in emulsions. SOFW Journal 138, 2-6, 2012
Lutz V, Sattler M, Gallinat S, Wenck H, Poertner R, Fischer F: Impact of collagen crosslinking on the second harmonic generation signal and the fluorescence lifetime of collagen autofluorescence. Skin Res Technol, 18: 168-179, 2012
Puschmann S, Rahn C, Wenck H, Gallinat S, Fischer F: Approach to quanitify human dermal skin aging using multiphoton laser scanning microscopy. J Biomed Opt. 17:036005, 2012
Hagmeister U, Reuschlein K, März A, Wenck H, Gallinat S, Lucius R, Knott A: Poly(A) tail shortening correlates with mRNA repression in tropoelastin regulation. J Dermatol Sci. 67:44-50, 2012
Brönneke S, Brückner B, Peters N, Bosch T, Stäb F, Wenck H, Hagemann S,Winnefeld M: DNA methylation regulates lineagespecifying genes in primary lymphatic and blood endothelial cells. Angiogenesis 15(2):317-29, 2012
Roggenkamp D, Falkner S, Stäb F, Petersen M, Schmelz M, Neufang G: Atopic Keratinocytes Induce Increased Neurite Outgrowth in a Coculture Model of Porcine Dorsal Root Ganglia Neurons and Human Skin Cells. J Invest Dermatol. 2012 Mar 15.
Navid F, Kolbe L, Stäb F, Korff T, Neufang G: UV radiation induces the release of angiopoietin-2 from dermal microvascular endothelial cells. Exp Dermatol. 21:147-53, 2012
Basketter DA Clewell H, Kimber I, Rossi A, Blaauboer B, Burrier R, Daneshian M, Eskes C, Goldberg A, Hasiwa N, Hoffmann S, Jaworska J , Knudsen TB, Landsiedel R, Leist M, Locke P, Maxwell G, McKim J, McVey EA, Ouédraogo G, Patlewicz G, Pelkonen O, Roggen E, Rovida C, Ruhdel I, Schwarz M, Schepky A, Schoeters G, Skinner N, Trentz K, Turner M, Vanparys P, Yager J, Zurlo J, Hartung T: A Roadmap for the Development of Alternative (Non-Animal) Methods for Systemic Toxicity Testing. ALTEX 29, 2012
Peirano R, Hamann T, Düsing H-J, Akhiani M, Koop U, Schmidt-Rose T, Wenck H: Topically applied L-carnitine effectively reduces sebum secretion in human skin. Journal of Cosm Dermatol, 11, 30-36, 2012
Peirano Ro I, Achterberg V, Düsing H-J, Akhiani M, Koop U, Jaspers S, Krüger A, Schwengler H, Hamann T, Wenck H, Stäb F, Gallinat S, Blatt T: Dermal penetration of creatine from a face-care formulation containing creatine, guarana and glycerol is linked to effective antiwrinkle and antisagging efficacy in male subjects. Journal of Cosmetic Dermatology, 10, 273-281, 2012
Enthaler, B, Pruns, J, Wessel, S, Rapp, C, Fischer, M, Wittern, KP, Improved sample preparation for MALDI–MSI of endogenous compounds in skin tissue sections and mapping of exogenous active compounds subsequent to ex-vivo skin penetration. Analytical and Bioanalytical Chemistry. 402: 1159-1167, 2012
Weber TM, Kausch M, Rippke F, Schoelermann AM, Filbry AW:Treatment of Xerosis with a Topical Formulation Containing Glyceryl Glucoside,Natural Moisturizing Factors, and Ceramide. J Clin Aesthet Dermatol 5: 29–39, 2012
Kuhlmann M, Hartkopf C, Span P, Kausch M, Wolber R: Treatment of dry, calloused feet. Skin care performance, efficacy and skin compatibility of a New Anti Callus Peeling, Cream and Serum. The Society of Chiropodists and Podiatrists , Poster Nov 2012, Glasgow, UK
Ceridono M, Tellner P, Bauer D, Barroso J, Alépée N, Corvi R, De Smedt A, Fellows MD, Gibbs NK, Heisler E, Jacobs A, Jirova D, Jones D, Kandárová H, Kasper P, Akunda JK, Krul C, Learn D, Liebsch M, Lynch AM, Muster W, Nakamura K, Nash JF, Pfannenbecker U, Phillips G, Robles C, Rogiers V, Van De Water F, Liminga UW, Vohr HW, Wattrelos O, Woods J, Zuang V, Kreysa J, Wilcox P. The 3T3 neutral red uptake phototoxicity test: Practical experience and implications for phototoxicity testing - The report of an ECVAM-EFPIA workshop. Regulatory Toxicology and Pharmacology 63: 480-488, 2012

2011

Matthias Vockel, Simone Pollok, Ute Breitenbach, Ina Ridderbusch, Hans-Jürgen Kreienkamp, Johanna M. Brandner: Somatostatin Inhibits Cell Migration and Reduces Cell Counts of Human Keratinocytes and Delays Epidermal Wound Healing in an Ex Vivo Wound Model. PLOS ONE, May 2011, Volume 6, Issue 5, e19740
S. Conzelmann, B. Traupe, R. I. Peirano, T. Schläger, F. rippke, G. Neufang: Clinical and Dermatological Studies on Medical Skin and wound Care. Poster Presentations at the 20th EADV Congress Lisbon 2011
Hetzel F, Rößler, K, Brummer, R: Rheo-optische Charakterisierung von kosmetischen Schäumen, Buchbeitrag "Seminarband Würzburger Tage 2010" ISBN 978-3-940184-08-5
Mess, A, Vietzke, JP, Rapp C, Franke, W: Qualitative analysis of tackifier resins in pressure sensitive adhesives using direct analysis in real time time-of-flight mass spectrometry. Analytical Chemistry (accepted 24.08.2011)
Meinke, M., Richter, H., Schanzer, S., Bohnsack, K., Presto, S., Filbry, A., Rippke, F., Vogt, A., Lademann, J.: Penetration of topically applied pollen allergens into Langerhans cells in barrier disrupted human skin and a prevention method. Exp. Dermatol. 2011, 20: 164
Grotheer, E., Heinsohn, G., Rapp, C., Presto, S., Rippke, F., Uhlmann, B., Conzelmann, S.: A novel method to educate patients how to apply a sufficient amount of sunscreen aided by in vivo attenuated total reflection FT-IR spectroscopic imaging. Exp. Dermatol. 2011, 20: 193
Schölermann, A., Scherdin, U., Filbry, A., Presto, S., Rippke, F.: Efficacy of three new anti-wrinkle face care creams with urea and hyaluronic acid. Exp. Dermatol. 2011, 20: 207
Scherdin, U., Traupe, B., Schulz, J., Presto, S., Rippke, F., Filbry, A.: Results of in vitro and in vivo studies with a novel shave and after shave regimen. Exp. Dermatol. 2011, 20: 207
S. Conzelmann, B. Traupe, R. I. Peirano, T. Schläger, F. Rippke, G. Neufang: A new skin care approach for acne prone skin, Poster EADV (2011)
K. Bohnsack, A.-K. Fiege, U. Dickschat, A. Filbry, F. Rippke, R. Fölster-Holst: Preventive efficacy of a skin care lotion containing Dexpanthenol, Glycerin and Citrate buffer on the exacerbation of allergic skin condition induced by birch pollen in atopic patients. Poster EADV (2011)
J. Kühnl, L. Gonda, N. Peters, L. Kolbe, F. Rippke, S. Conzelmann, F. Stäb, G. Neufang: Protective efficacy in PLE by alpha-Glucosylrutin plus Licochalcone A. Poster EADV (2011)
A. Mahns, M. Hong, J. Batzer, F. Staeb, T. Mann, W. Gerwat, C. Scherner, F. Rippke, L. Kolbe: Glycyrrhetinic acid significantly enhances the repair of UV-induced cyclobutane-pyrimidine-dimers in human skin. Poster EADV (2011)
Kuhlmann M, Hartkopf C, Wolber R: Assessment of local tolerability and wound healing properties of first aid dressings in sensitive, mature skin and diabetics in a suction blister wound model. Poster EADV (2011)
Ruetze M, Dunckelmann K, Schade A, Reuschlein K, Mielke H, Weise JM, Gallinat S, Wenck H, Knott A. Damage at the root of cell renewal-UV sensitivity of human epidermal stem cells. J Dermatol Sci. 2011 Jun 30. [Epub ahead of print]
Lutz V, Sattler M, Gallinat S, Wenck H, Poertner R, Fischer F. Impact of collagen crosslinking on the second harmonic generation signal and the fluorescence lifetime of collagen autofluorescence. Skin Res Technol. 2011 May 12. [Epub ahead of print]
Ito S, Nakanishi Y, Valenzuela RK, Brilliant MH, Kolbe L, Wakamatsu K. Usefulness of alkaline hydrogen peroxide oxidation to analyze eumelanin and pheomelanin in various tissue samples: application to chemical analysis of human hair melanins. Pigment Cell Melanoma Res. 2011 Aug; 24(4):605-13.
Fischer F, Achterberg V, März A, Puschmann S, Rahn CD, Lutz V, Krüger A, Schwengler H, Jaspers S, Koop U, Blatt T, Wenck H, Gallinat S. Folic acid and creatine improve the firmness of human skin in vivo. J Cosmet Dermatol. 2011 Mar;10(1):15-23.
Scheede S, Herpens A, Burmeister F, Oltrogge B, Saenger K, Schmidt-Rose T, Schreiner V, Wenck H, Knieps T, Berlage T. Qualification of a new and precise automatic tool for the assessment of hair diameters in phototrichograms. Skin Res Technol. 2011 May;17(2):186-95.
Schmidt-Rose T, Braren S, Fölster H, Hillemann T, Oltrogge B, Philipp P, Weets G, Fey S. Efficacy of a piroctone olamine/climbazol shampoo in comparison with a zinc pyrithione shampoo in subjects with moderate to severe dandruff. Int J Cosmet Sci. 2011 Jun;33(3): 276-82.
Spörl F, Schellenberg K, Blatt T, Wenck H, Wittern KP, Schrader A, Kramer A. A circadian clock in HaCaT keratinocytes. J Invest Dermatol. 2011 Feb;131(2):338-48.
Reuter H, Spieker J, Gerlach S, Engels U, Pape W, Kolbe L, Schmucker R, Wenck H, Diembeck W, Wittern KP, Reisinger K, Schepky AG. In vitro detection of contact allergens: development of an optimized protocol using human peripheral blood monocyte-derived dendritic cells. Toxicol In Vitro. 2011 Feb;25(1):315-23.
Hildebrand J, Rütze M, Walz N, Gallinat S, Wenck H, Deppert W, Grundhoff A, Knott A. A comprehensive analysis of microRNA expression during human keratinocyte differentiation in vitro and in vivo. J Invest Dermatol. 2011 Jan;131(1):20-9.
Shosuke Ito, Yukiko Nakanishi, Robert K. Valenzuela, Muray H. Brilliant, Ludger Kolbe and Kazumasa Wakamatsu: Pigment Cell & Melanoma Research, DOI: 10.1111/j.1755-148x.2011.000864.x Volume 24, Issue 4, Pages 605-613
Knott A., Drenckhan A., Reuschlein K., Lucius R., Stäb F., Wenck H., Gallinat S.: Decreased fibroblast contractile activity and reduced fibronectin expression are involved in skin photoaging, Poster FEBS 2011, Spetses
J. Kühnl, L. Gonda, N. Peters, L. Kolbe, F. Stäb, G. Neufang: alpha-Glucosylrutin plus Licochalcone A: Enhanced Protective Efficacy in PLE, WCD 2011, Seoul
M. Hong, J. Batzer, A. Mahns, T. Mann, W. Gerwat, C. Scherner, R. Wolber, F. Stäb, L. Kolbe: Modulation of DNA-Repair in UV-Irradiated Human Skin by Glycyrrhetinic Acid, WCD 2011, Seoul
Meinke, M., Patzelt, A., Richter, H., Schanzer, S., Sterry, W., Filbry, A., Bohnsack, K., Rippke, F., Galecka, J., Fölster-Holst, R., Lademann, J.: Prevention of Follicular Penetration: Barrier-Enhancing Formulations against the Penetration of Pollen Allergens into Hair Follicles. Skin Pharmacol. Physiol. 2011; 24: 144-150
S. Presto, F. Rippke, A. Schölermann, A. Filbry, W. Mei, F. L. Xiang: The efficacy of Medical Skincare Products in Chinese Patients with Impure, Acne-prone Skin, WCD 2011, Seoul
Martin A, Hellhammer J, Hero T, Max H, Schult J, Terstegen L. Effective prevention of stress-induced sweating and axillary malodour formation in teenagers. Int J Cosmet Sci. 2011 Feb;33(1):90-7.
Bilgram V, Biel S: Getting closer to the consumer – how Nivea co-creates new products. Marketing Review St. Gallen 1/2011, 34-40 (2011)
Miller D, Koch S, Yentzer B, Clark A, O’Neill J, Fountain J, Weber TM, Fleischer AB: An over-the-counter moisturizer is as clinically effective as, and more cost-effective than, prescription barrier creams in the treatment of children with mild to moderate atopic dermatitis: a randomized, controlled trial. J Drugs Dermatol. 2011: 5:29-39
Trookman NS, Rizer RL, Weber TM: Treatment of minor wounds from dermatological procedures: A comparison of three topical wound care ointments using a laser wound model. J Amer Acad Dermatol, 2011: 64: S8-S15
Trookman NS, Rizer RL, Weber TM: Irritation and allergy patch test analysis of topical treatments commonly used in wound care: Evaluation of normal and compromised skin. J Amer Acad Dermatol 2011, 64: S16-S22
Weber TM, Schoelermann AM, Breitenbach U, Scherdin U, Kowcz A: Hand and Foot Moisturizers. In Cosmetic Dermatology: A Comprehensive Medical and Surgical Text; Draelos ZD, Ed. Wiley-Blackwell: Oxford 2010, pp 130-138

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